Advances in Virus Research, Vol. 72 by Karl Maramorosch, Aaron J. Shatkin, Frederick A. Murphy

By Karl Maramorosch, Aaron J. Shatkin, Frederick A. Murphy

Released in view that 1953, Advances in Virus study covers a various diversity of in-depth reports supplying a helpful review of the present box of virology. The impression issue for 2006 is 3.48 putting it seventh within the hugely aggressive classification of virology. * Contributions from prime experts * Informs and updates on all of the most recent advancements within the box

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2006). , 1985). Dengue virus TOT has been also demonstrated in other Aedes mosquito species that play a role in the transmission of DENV in nature, such as Ae. , 1985), Ae. mediovittatus (Freier and Rosen, 1988), and several members of the Aedes (Stegomyia) scutellaris group, which are important in the transmission of DENV in the Indonesian archipelago and Polynesia (Freier and Rosen, 1987). However, TOT rates in Ae. , 1997). Interestingly, at least for Ae. , 2002) in the absence of any horizontal transmission from vertebrate blood meals, a notion initially suggested by Rosen 15 years earlier (Rosen, 1987).

1999). Similarly DENV-3 genotype III, which belongs to a genetically distinct clade (Fig. , 2003). , 2001). , 2008c). Of particular interest is a particular amino acid difference at position 390 of the E protein, which has been suggested to be a critically determinant of virulence. , 1996). , 2008c). , 2001) and moDCs (Cologna and Rico-Hesse, 2003), as well as to alter virulence for mice (Sanchez and Ruiz, 1996). The putative attenuating property of D390 is further enhanced in chimeras where the Asian genotype 30 -NCR is replaced with the American genotype 30 -NCR (Cologna and Rico-Hesse, 2003), suggesting a synergistic function.

The calculated minimum field infection rates were 1:2067 and 1:3865 respectively (Khin and Than, 1983). Low filial infection rates for Ae. , 1983). Further evidence of TOT, was also obtained in Trinidad were DENV-4 was isolated in a pool of adult Ae. , 1996). More recently, field-caught male Ae. , 2006). , 1985). Dengue virus TOT has been also demonstrated in other Aedes mosquito species that play a role in the transmission of DENV in nature, such as Ae. , 1985), Ae. mediovittatus (Freier and Rosen, 1988), and several members of the Aedes (Stegomyia) scutellaris group, which are important in the transmission of DENV in the Indonesian archipelago and Polynesia (Freier and Rosen, 1987).

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